The Serum Run: Howling Winds and the Hand Off

A limited series based on the 1925 Serum Run in Alaska, hosted by Alex Stein. On this episode: Howling Winds and the Hand Off. 

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This episode of Dog Works Radio tells the story of the 1925 Serum Run, a heroic dog sled relay that delivered life-saving diphtheria antitoxin to the town of Nome, Alaska. The chapters cover the introduction and sponsorship, the background of the Serum Run, the start of the journey, the challenges faced on the trail, Togo’s heroic act, the ice flow dilemma, Togo’s rescue, the arrival at Isaacs Point Lighthouse, preparing for the final leg, and a preview of the next episode. The episode concludes with sponsorship messages.


  • The 1925 Serum Run was a remarkable dog sled relay that delivered life-saving diphtheria antitoxin to Nome, Alaska.

  • The mushers and their dogs faced extreme weather conditions, including temperatures as low as 64 degrees below zero and wind gusts of over 100 miles per hour.

  • Togo, a lead dog, played a crucial role in the success of the Serum Run, including rescuing the antitoxin from an ice flow.

  • The Serum Run demonstrated the incredible bond between mushers and their dogs and the determination and bravery required to save lives.


00:00: Introduction and Sponsorship
01:2: 0Background on the 1925 Serum Run
02:02: The Journey Begins
03:25: Challenges on the Trail
04:16: Togo Saves the Day
06:05: The Ice Flow Dilemma
08:17: Togo’s Heroic Act
10:41: Arrival at Isaacs Point Lighthouse
12:05: Preparing for the Final Leg
13:29: Next Week: Racing the Storm
13:42: Sponsorship and Conclusion